Tottenham survived a major scare at Molineux as a 3-0 lead became a narrow 3-2 advantage, but they held on for a victory that leaves them just three points off the top of the table.
The loss of the midfielder, who will undergo assessment on Sunday, aided Wolves in briefly establishing a foothold prior to Erik Lamela and Lucas Moura's quickfire first-half goals.
Spurs had any momentum knocked out of them when they lost Dembele inside the first 10 minutes.
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It is widely believed that the meeting between the two leaders will focus on resolving the trade issue between China and the US. Hong Kong's Hang Seng Index surged more than 4% while China's Shanghai Composite and Japan's Nikkei both jumped about 2.5%.
But the visitors had regained their composure and netted two goals in three minutes.
Tottenham are next in action in the Champions League on Tuesday night at home against PSV Eindhoven, while their next Premier League game comes at Selhurst Park against Crystal Palace. Harry Winks and Moussa Sissoko have a busy week ahead.
"We play football to the end, sometimes we get rewarded and sometimes we don't". He did the best he could in the circumstances. He was then lucky when, having allowed Costa to run through on goal, his opponent prodded a shot wide.
The hosts were awarded a second penalty in the 77th minute as Juan Foyth committed another foul in the box.
"I think both options could be important for Real Madrid".
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Gray's goal saw Leicester beat Cardiff 1-0 in their first match since Srivaddhanaprabha died in a helicopter crash last Saturday. Goals from Erik Lamela, Lucas Moura and Harry Kane appeared to put Tottenham in an unassailable position at Wolverhampton.
DF Ben Davies, 5 - Struggled against Matt Doherty throughout and, once again, offered precious little in possession.
"Perez wasn't expecting that things could go so wrong so quickly this season", he said.
On an evening when the depth of his squad seemed at risk of being exposed with an injury to Mousa Dembele and a shaky Premier League debut by Juan Foyth, Tottenham manager Mauricio Pochettino saw his side nearly contrive to throw away a 3-0 lead. "They are suffering up front, scoring very few goals and Kane could be the solution".
Central to Wolves strength this season has been the coach Nuno Espirito Santo who has stuck with the same starting line up for the majority of the campaign so far.
He was replaced from the substitutes' bench by Son Heung-Min in a change that forced a reshuffle, with Moussa Sissoko moving to his less favoured holding midfield role.
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The strain found in the Wanaque rehab center outbreak is called type 7 and is among the more potent types. The paper said civilian outbreaks were not frequently reported because of a lack of lab resources.
"The decision was to bring on Son [Heung-Min], but he played 90 minutes on Wednesday".