Officers were searching the area Monday night for suspects "who we believe are armed and risky", Police Chief Terrence Sheridan noted earlier.
A Baltimore County police official said the officer was shot around 2 p.m. while responding to a call for suspicious vehicle on Linwen Way, according to WBAL.
The officer would have been a four-year veteran in July.
Authorities say a Baltimore County police officer who was fatally injured while investigating a suspicious vehicle had been on the force for nearly four years. Several people tried to keep her alive, but she was later pronounced dead at a hospital.
"Officers who have died at the hands of gunshots is up", Sheridan said.
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Police tweeted that residents in the area of Belair and Klausmeier roads should shelter in place as officers search for an armed suspect.
Vinson said police discovered damage to a rear patio door of a home in the area, indicating the officer may have interrupted a burglary in progress.
"The next thing he heard was a pop, and he saw the Jeep take off and run right over her", he said. We're seeing police officers assaulted. His fellow officer died in the incident. "And so we're telling everybody to be on your toes, don't be complacent, to work with each other".
The police chief said that Americans are "seeing something in this country we've never seen before".
The unnamed officer was responding to a report of a suspicious vehicle near the Perry Hall area around 2pm when the shooting took place.
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"What exactly happened we are not sure yet until an autopsy is performed", Vinson said at a press conference Monday.
State and federal authorities are assisting at the scene, Vinson said. "We are proud of the bravery and courage and sacrifice of all the men and women who serve on our police force".
Witnesses reported hearing a pop and seeing the officer run over by a Jeep, The Associated Press writes.
Volunteer firefighter Logan Kurek says he ran outside and performed CPR on the officer until paramedics arrived, and says her injuries were consistent with being run over by a auto.
Marks also said schools nearby were locked down. Drivers were advised to avoid the area. But by Monday evening, parents were allowed to come to the schools to pick up their youngsters.
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Students at three local elementary schools were held over on alert status for the entire afternoon because of police activity.